ANGPTL8 Blockade With a Monoclonal Antibody Promotes Triglyceride Clearance, Energy Expenditure, and Weight Loss in Mice
نویسندگان
چکیده
منابع مشابه
Resting energy expenditure changes with weight loss: racial differences.
It is controversial whether weight loss reduces resting energy expenditure (REE) to a different magnitude in black and white women. This aim of this study was to determine whether changes in REE with weight loss were different between black and white postmenopausal women, and whether changes in body composition (including regional lean and fat mass) were associated with REE changes within each ...
متن کاملChanges in Energy Expenditure with Weight Gain and Weight Loss in Humans
Metabolic adaptation to weight changes relates to body weight control, obesity and malnutrition. Adaptive thermogenesis (AT) refers to changes in resting and non-resting energy expenditure (REE and nREE) which are independent from changes in fat-free mass (FFM) and FFM composition. AT differs in response to changes in energy balance. With negative energy balance, AT is directed towards energy s...
متن کاملHeat shock factor 5 is essential for spermatogenesis in mice: Detected by a new monoclonal antibody
Objective(s): Here, we examined the function of our produced monoclonal antibody (mAb10C3) to recognize one of the most important members of the HEAT shock factor family, Hsf5, in embryonic development and in spermatogenic cells of adult mouse testis.Materials and Methods: The targeting effects of mAb10C3 were investigated by immunohisto...
متن کاملEffects of diet cycling on weight loss, fat loss and resting energy expenditure in women
Background The Curves fitness program involves a 30-minute circuit training program. Women interested in losing weight can also follow a weight management program. The most recent version of the weight management program involves cycling between periods of moderate calorie restriction (1,200 – 1,500 kcals/d) followed by periods of higher caloric intake (2,200 kcals/d) in an attempt to prevent l...
متن کاملEnergy expenditure, insulin, and VLDL-triglyceride production in humans.
Hypertriglyceridemia is considered a cardiovascular risk factor in diabetic and nondiabetic subjects. In this study, we aimed to determine potential regulators of very low density lipoprotein-triglyceride (TG) production. VLDL-TG kinetics were measured in 13 men and 12 women [body mass index [mean (range)]: 24.8 (20.2-35.6) kg/m(2)]. VLDL-TG production was assessed from the plasma decay of a bo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrinology
سال: 2017
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2016-1894